This study aims to evaluate the impact of a safe-space based life skills training program and a combination of life skills and digital literacy training programs on adolescent girls’ empowerment, education, economic, and reproductive health outcomes. The interventions form two sub-components of the Adolescent Girls’ Initiative for Learning and Empowerment project. The sample covered randomly selected secondary school girls between the ages of 15 and 20 in rural and semi-urban schools that were eligible for the safe space-based life skills and digital skills trainings. The baseline data was collected through face-to-face interviews with 8,223 adolescents, 8,007 caregivers, and 270 school principals across Kaduna, Kano and Katsina States. The field data collection occurred simultaneously across the three States and lasted for 44 days between April and June, 2023. Enumerators collected data with tablets containing programmed questionnaires on SurveyCTO platform.