To understand the socio-economic impact of COVID-19 and associated government measures over the long term, the fourth round of the COVID-19 National Panel Phone Survey 2020 was collected by the National Institute of Statistics of Djibouti (INSD) between March 11 and April 25, 2021. Various channels of impact are explored such as job loss, availability and price changes of basic food items, ability to access healthcare and education, food insecurity. The survey also includes a section on gender issues, including time-use and decision making, as well as a section on attitudes towards COVID-19 Vaccine. Within households, a respondent was chosen at random between the household heads and spouses, allowing comparison between female and male respondents in the sample. Further, the education questions are asked for a randomly chosen boy or girl within the households that have children.