The Cambodia Demographic and Health Survey in 2010 (CDHS 2010) is the third nationally representative survey conducted in Cambodia on population and health issues. It uses the same methodology as its predecessors, the 2000 and the 2005 Cambodia Demographic and Health Surveys, allowing policymakers to use these surveys to assess trends over time. The primary objective of the CDHS is to provide the Ministry of Health (MOH), Ministry of Planning (MOP), and other relevant institutions and users with updated and reliable data on infant and child mortality, fertility preferences, family planning behavior, maternal mortality, utilization of maternal and child health services, health expenditures, women’s status, and knowledge and behavior regarding HIV/AIDS and other sexually transmitted infections. This information contributes to policy decisions, planning, monitoring, and program evaluation for the development of Cambodia at both the national and local government levels.